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The Role of BTK in TLR Signaling

✍ Scribed by Marron, T.U.


Book ID
119281520
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
45 KB
Volume
123
Category
Article
ISSN
1097-6825

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Role of Btk in B cell development and si
✍ Stephen Desiderio πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 English βš– 669 KB

Bruton's tyrosine kinase (Btk), the target of inactivating mutations in X-linked immunodeficiency diseases of mice and humans, is essential for normal B cell responsiveness. Recent studies have outlined a mechanism for the activation of Btk by B cell receptor engagement and have identified proximal