Triflate ion-promoted addition reactions of allylsilane to quinolines and isoquinolines acylated by chloroformate esters

✍ Scribed by Ryohei Yamaguchi; Bunpei Hatano; Tatsuya Nakayasu; Sinpei Kozima

• Book ID: 104256058
• Publisher: Elsevier Science
• Year: 1997
• Tongue: French
• Weight: 209 KB
• Volume: 38
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(96)02310-6

✦ Synopsis

Reaction of allyltrimethylsilane with a variety of quinolines acylated by chloroformate esters can be promoted by a catalytic amount of a triflate ion to afford 2-allyl-l,2-dihydroquinolines in good to high yields. A similar reaction with isoquinolines afforded benzoisoquinuclidine derivatives by consumption of 2 eq of allyltrimethylsilane.