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Tricyclic antidepressant drugs as antagonists of muscarinic receptors in sympathetic ganglia

✍ Scribed by Marta Weinstock; Dvora Cohen


Book ID
118322005
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
600 KB
Volume
40
Category
Article
ISSN
0014-2999

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The binding kinetics of tritiated quinuclidinyl benzilate (QNB) were studied in membrane preparations from human parotid and rabbit submandibular glands. Inhibition of 3H-QNB was then used to compare the anticholinergic activity of lofepramine, desipramine, imipramine and amitriptyline for muscarini