Triazolo[4,5-d]pyrimidine Derivatives as Inhibitors of GCN2
✍ Scribed by Brazeau, Jean-Francois; Rosse, Gerard
- Book ID
- 121506334
- Publisher
- American Chemical Society
- Year
- 2014
- Tongue
- English
- Weight
- 158 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1948-5875
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## Abstract The 7‐chloro‐3‐(2‐chlorobenzyl)‐ and 7‐chloro‐3‐(2‐fluorobenzyl)‐1,2,3‐triazolo[4,5‐__d__]pyrimidines (**1** and **4**), by nucleophilic replacement with some hydrazides, gave the corresponding 7‐hydrazidoderivatives (**2a‐e** and **5a‐e**). These, by heating in Dowtherm, underwent an i
This article covers all the research work published until September 1998 about the coordination chemistry of 1,2,4-triazolo-[1,5-a]pyrimidine derivatives. The revision is mainly focused in the structural features of the compounds, obtained from single crystal X-ray diffraction. The references are cl