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Treosulfan-based conditioning regimens for hematopoietic stem cell transplantation in children with primary immunodeficiency: United Kingdom experience

✍ Scribed by Slatter, M. A.; Rao, K.; Amrolia, P.; Flood, T.; Abinun, M.; Hambleton, S.; Nademi, Z.; Goulden, N.; Davies, G.; Qasim, W.

Book ID: 115541861
Publisher: American Society of Hematology
Year: 2011
Tongue: English
Weight: 373 KB
Volume: 117
Category: Article
ISSN: 0006-4971
DOI: 10.1182/blood-2010-10-312082

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## Background To expand access to allogeneic haematopoietic stem cell transplantation (allo-HSCT) to patients who are ineligible for conventional myeloablative FTBI-or busulfan-based preparative regimens, the idea of reduced intensity conditioning (RIC) in the early 1990s, and somewhat later in th