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Tremor-correlated spike activity in Parkinson’s disease detected in a distributed subthalamic network

✍ Scribed by A. Florian; K. Henschel; B. Schelter; M. Winterhalder; B. Guschlbauer; B. Hellwig; J. Vesper; J. Timmer; C.H. Lücking

Book ID
118434342
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
35 KB
Volume
118
Category
Article
ISSN
1388-2457

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The role of the subthalamic nucleus (STN) in the origin of parkinsonian tremor is discussed. Previous studies in monkeys made parkinsonian by MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) administration suggested a direct participation of the STN in the pathophysiology of tremor. We recorded t