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Treatment with prostaglandins reduces the antifertility effect of indomethacin in rabbits

✍ Scribed by Amin A. El-Banna

Book ID
113379147
Publisher
Elsevier Science
Year
1986
Weight
365 KB
Volume
85
Category
Article
ISSN
0306-4492

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## Abstract The interaction between indomethacin (IND) and methotrexate (MTX) was investigated in rabbits. The study was designed so as to evaluate the effect of IND (1 mg h^βˆ’1^) during a continuous MTX infusion (1Β·2 mg kg^βˆ’1^) over 240 min. IND was injected i.v. at hourly intervals after a steady