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Reduction by indomethacin of furosemide effects in the rabbit

✍ Scribed by Ernst Oliw; Georges Kövér; Carin Larsson; Erik Änggård

Book ID
118322105
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
418 KB
Volume
38
Category
Article
ISSN
0014-2999

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## Abstract The interaction between indomethacin (IND) and methotrexate (MTX) was investigated in rabbits. The study was designed so as to evaluate the effect of IND (1 mg h^−1^) during a continuous MTX infusion (1·2 mg kg^−1^) over 240 min. IND was injected i.v. at hourly intervals after a steady