Treatment with N-methyl-d-aspartate receptor antagonist (MK-801) protects against oxidative stress in lipopolysaccharide-induced acute lung injury in the rat
✍ Scribed by Aline Andrea da Cunha; Fernanda Bordignon Nunes; Adroaldo Lunardelli; Vânia Pauli; Robson Henrich Amaral; Luciana Mello de Oliveira; Vasyl Custódio Saciura; Gabriela Lucas da Silva; Melissa Guerra Simões Pires; Márcio Vinícius Fagundes Donadio; Denizar Alberto da Silva Melo; Felipe Dal-Pizzol; José Cláudio Fonseca Moreira; Guilherme Antonio Behr; Carlos Luiz Reichel; Jose Luis Rosa; Jarbas Rodrigues de Oliveira
- Book ID
- 116576848
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 246 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1567-5769
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The present study shows that systemic administration of the selective, non-competitive N-methyl-D-aspartate antagonist MK-801 [(+)-5-methyl-10,11-dihydroxy-5H-dibenzo (a,d)-cyclohepten-5,10-imine] dose-dependently induces ipsiversive rotational behavior in the rats with a unilateral striatal lesion