CD154 is the ligand for the receptor CD40. This ligand-receptor pair mediates endothelial and antigen-presenting cell activation, and facilitates the interaction of these cells with T cells and platelets. We demonstrate here that administration of a CD154-specific monoclonal antibody (hu5C8) allows
โฆ LIBER โฆ
Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates
โ Scribed by Kirk, Allan D.; Burkly, Linda C.; Batty, D. Scott; Baumgartner, Roxanne E.; Berning, Justin D.; Buchanan, Kelvin; Fechner, John H.; Germond, Rhonda L.; Kampen, Robert L.; Patterson, Noelle B.; Swanson, S. John; Tadaki, Douglas K.; TenHoor, Christopher N.; White, Leonard; Knechtle, Stuart J.; Harlan, David M.
- Book ID
- 109832167
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 688 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1078-8956
- DOI
- 10.1038/9536
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