Treatment with anakinra in the hyperimmunoglobulinemia D/periodic fever syndrome
β Scribed by Donato Rigante; Valentina Ansuini; Barbara Bertoni; Anna Lisa Pugliese; Laura Avallone; Gilda Federico; Achille Stabile
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 203 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0172-8172
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## Abstract We describe for the first time a case of macrophage activation syndrome in a child with hyperimmunoglobulinemia D with periodic fever syndrome who required intensive care support. Upβregulated monokine production, high serum levels of triglycerides and ferritin, clotting abnormalities w
## Abstract Systemic reactive (AA) amyloidosis, leading to renal failure, is a severe complication of most hereditary periodic fever syndromes. The risk of developing this lifeβthreatening condition varies widely among these disorders, being higher for patients affected by familial Mediterranean fe