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Treatment of Transforming Growth Factor-Beta-Insensitive Mouse Renca Tumor by Transforming Growth Factor-Beta Elimination

✍ Scribed by Kent Perry; Larry Wong; Victoria Liu; Irwin Park; Qiang Zhang; Varun Rejen; Xuemei Huang; Norm D. Smith; Borko Jovanovic; Scott Lonning; Beverly A. Teicher; Chung Lee

Book ID
116948976
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
196 KB
Volume
72
Category
Article
ISSN
0090-4295

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## Abstract Pronounced changes including growth inhibition, increased matrix deposition and suppression of cell‐associated proteolytic activity, take place in endothelial cells (EC) upon the application of TGF‐β. Interrelationships between these effects have shed some light on the mechanism of acti