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Treatment of thrombotic thrombocytopenic purpura

✍ Scribed by Menno van der Straaten; Sophie Jamart; Robert Wens; Philippe Gottignies; Max Dratwa; Jacques Devriendt

Publisher
Springer
Year
2005
Tongue
English
Weight
80 KB
Volume
31
Category
Article
ISSN
1432-1238

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Five patients with thrombotic thrombocytopenic purpura (TTP) were treated with corticosteroids, plasma exchange (PE), and antiplatelet agents. ABO-and Rh-compatible fresh-frozen plasma (FFP) was used as the replacement fluid. None of the patients received FFP infusion without PE. The patients were

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Plasma exchange (PE) is considered first-line treatment for thrombotic thrombocytopenic purpura (TTP) to the point that many clinicians regard it as definitive therapy. Studies have reported response rates to PE ranging from 39% to 78%. In our experience, a minority of patients have been cured solel