Successful treatment of thrombotic thrombocytopenic purpura with high-dose corticosteroid
โ Scribed by Michihiro Toyoshige; Yuzuru Zaitsu; Koichiro Okafuji; Yasushi Inoue; Yukio Hiroshige; Noboru Matsumoto; Kohei Kaku; Toshio Kaneko
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 116 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0361-8609
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๐ SIMILAR VOLUMES
The objective of this study was to assess the effect of protein A immunoabsorption in terms of response rate and toxicities in patients with classical thrombotic thrombocytopenic purpura (TTP) refractory to therapeutic plasma exchange. The study included nine females and one male with a diagnosis of
Idiopathic thrombocytopenic purpura (ITP) is refractory to initial treatment (steroids and splenectomy) in 25 to 30% of patients. These patients have a significant risk of fatal hemorrhage. Two patients with ITP refractory to multiple interventions and severe depression of platelet counts responded