Treatment of solid tumors with immunotoxins
β Scribed by Davorka Messmer, Thomas J Kipps
- Book ID
- 120700006
- Publisher
- BioMed Central
- Year
- 2005
- Tongue
- English
- Weight
- 44 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1465-5411
- DOI
- 10.1186/bcr1284
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An animal model has been established to investigate the effect of intra-thecal (i.t.) immunotoxins in the treatment of leptomeningeal metastases of acute lymphoblastic leukaemia (ALL). Direct inoculation of b C lymphoma cells into the cisterna ma na of guinea-pigs gives rise to a leptomeningeal patt