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Treatment of severe hypercholesterolemia with heparin-induced LDL apheresis

✍ Scribed by Werner O. Richter; Bernd Jacob; Michael M. Ritter; Klaus Sühler; Karin Vierneisel; Peter Schwandt

Book ID
117090633
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
714 KB
Volume
52
Category
Article
ISSN
0011-393X

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Familial hypercholesterolemia (FH) is an inherited disorder of lipoprotein metabolism involving mutations in the LDL receptor (LDL-R). Patients with mutation in one (heterozygous) or both (homozygous) genes have markedly elevated LDL cholesterol and are at increased risk for coronary heart disease (