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Ex-vivo and in-vivo platelet function in patients with severe hypercholesterolemia undergoing LDL-apheresis

✍ Scribed by Helmut Sinzinger; Christian Pirich; Judith Bednar; John O'Grady


Book ID
116087144
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
755 KB
Volume
82
Category
Article
ISSN
0049-3848

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Familial hypercholesterolemia (FH) is an inherited disorder of lipoprotein metabolism involving mutations in the LDL receptor (LDL-R). Patients with mutation in one (heterozygous) or both (homozygous) genes have markedly elevated LDL cholesterol and are at increased risk for coronary heart disease (