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Experimental and in vivo stimulation of LDL receptor expression in atorvastatin treated patients with heterozygous familial hypercholesterolemia by LDL-immunoapheresis


Book ID
118630714
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
152 KB
Volume
3
Category
Article
ISSN
1567-5688

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During a survey of Italian patients with familial hypercholesterolemia (FH), we identified an FH heterozygous patient with a gross rearrangement of the low density lipoprotein (LDL) receptor gene. Southern blot analysis of the proband's DNA digested with restriction enzymes PvuII, BamHI, BglII and X