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Treatment of Renal Cell Carcinoma in Von Hippel-Lindau Disease: A Multicenter Study

✍ Scribed by Steinbach, Frank; Novick, Andrew C.; Zincke, Horst; Miller, Dave P.; Williams, Richard D.; Lund, Greg; Skinner, Donald G.; Esrig, David; Richie, Jerome P.; DeKernion, Jean B.; Marshall, Fray; Marsh, Christopher L.


Book ID
121195463
Publisher
Lippincott Williams and Wilkins
Year
1995
Tongue
English
Weight
517 KB
Volume
153
Category
Article
ISSN
0022-5347

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Copy number profiling in von hippel-lind
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## Abstract Germline mutations in the __VHL__ tumor suppressor gene cause von Hippel‐Lindau (VHL) disease and somatic __VHL__ mutations occur in the majority of clear cell renal cell carcinoma (cRCC). To compare copy number abnormalities (CNAs) between cRCC from VHL patients and sporadic cRCC cases