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Treatment of primary herpes simplex virus infection in guinea pigs by imiquimod

✍ Scribed by Richard L. Miller; Linda M. Imbertson; Michael J. Reiter; John F. Gerster


Book ID
114145250
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
98 KB
Volume
44
Category
Article
ISSN
0166-3542

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## Abstract Factors that influence the outcome of genital herpes simplex virus (HSV) infection were explored in a guinea pig model. The viral inoculum required to establish infection in 50% of animals (ID~50~) was similar for inbred (strain 2) and out‐bred (Hartley) guinea pigs. However, the viral