Treatment of patients with metastatic germ cell tumors relapsing after high-dose chemotherapy
β Scribed by C. Kollmannsberger; F. Mayer; M. Kuczyk; L. Kanz; C. Bokemeyer
- Publisher
- Springer-Verlag
- Year
- 2001
- Tongue
- English
- Weight
- 89 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0724-4983
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## BACKGROUND. The optimal treatment of patients with recurrent or refractory germ
During the past 10 years, high-dose chemotherapy (HDCT) has emerged as a feasible and curative treatment option for patients with multiply relapsed and/or refractory germ-cell tumors. Increasing experience and the results from clincial trials have helped to optimize the application of HDCT and to de
## Germ -cell tumors (GCTs) are very chemosensitive and highly curable cancers. For the small proportion of patients who fail conventional chemotherapy (CT), high-dose CT (HDCT) was introduced in France and elsewhere in 1982-1984. We report here on the French experience with HDCT in GCTs. At the C
## Abstract ## BACKGROUND Highβdose chemotherapy (HDCT) followed by hematopoietic stem cell support (HSCS) potentially may be curative in patients with germ cell tumor (GCT) who develop recurrent tumors or who have an inadequate response after receiving standardβdose chemotherapy. The authors repo