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Treatment of low-grade B-cell lymphoma with the monoclonal antibody rituximab

โœ Scribed by Robert O Dillman


Book ID
114106626
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
136 KB
Volume
30
Category
Article
ISSN
0093-7754

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Treatment of B-cell non-Hodgkin's lympho
โœ Stefano Sacchi; Massimo Federico; Giuseppe Dastoli; Claudia Fiorani; Giovanni Vi ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 232 KB

Rituximab is a chimeric anti CD-20 monoclonal antibody containing human IgG1 kappa constant regions, with murine variable regions. The anti-lymphoma effects of Rituximab are probably due to complement and antibody-dependent cell-mediated cytotoxicity, and induction of apoptosis. Phase II trials have