HLA system affects the age-at-onset in c
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Fatma Savran Oguz; Sevgi Kalayoglu; A. Sarper Diler; Hilmi Tozkir; Deniz Sargin;
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Article
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2003
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John Wiley and Sons
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English
β 106 KB
π 1 views
## Abstract Chronic myeloid leukemia (CML) occurs from childhood to old age. The adult form is characterized by the presence of Philadelphia chromosome resulting from bcr/abl translocation. The BCRβABL fusion proteins are immunogenic, and the junctional sequences show unique HLA class I and class I