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Treatment of giant cell granuloma of the maxilla with intralesional injection of steroids

โœ Scribed by Avi Khafif; Greg Krempl; Jesus E. Medina

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
140 KB
Volume
22
Category
Article
ISSN
1043-3074

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โœฆ Synopsis

Background. Giant cell granuloma is rare in the head and neck region and most commonly affects the maxilla and mandible. Although it is a benign disease process, it may be locally destructive. Surgery is the treatment currently recommended. Because of the location of the disease, surgery may be disfiguring. Because it is a benign process, less radical nonsurgical treatment alternatives are desirable.

Methods. A case report of a giant cell granuloma treated with steroid injections.

Results. After six weekly intralesional steroid injections, a giant cell granuloma of the maxilla became calcified and smaller. After a follow-up period of 2 years, there was no evidence of regrowth, and the bony osteolytic lesion had filled with bone. A review of the literature revealed two case reports of successful steroid injections with similar response.

Conclusions. Steroid injections are a viable alternative in the treatment of giant cell granuloma, which may avoid surgery.

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