Interferon therapy in cirrhotic patients with hepatitis C virus infection is not efficient. In an at- tempt t o improve the response rate, a pilot study using recombinant human granulocyte colonystimulating factor (rhG-CSF) alone, and in combination with recombinant interferon-alpha (rlFN), was carr
Treatment of chronic hepatitis B with recombinant interferon alpha versus recombinant interferon alpha plus levamisole
✍ Scribed by Orencio Bosch; Gloria Moraleda; Inmaculada Castillo; Vicente Carreño
- Book ID
- 118566410
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 345 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0168-8278
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Eight patients with chronic hepatitis B entered a pilot study of gamma interferon and alpha interferon in combination. Gamma interferon alone had minimal inhibitory effects on serum levels of hepatitis B virus as monitored by serum HBV DNA and DNA-polymerase activity. The drug also gave troublesome
We have investigated the efficacy of a relatively prolonged course of recombinant leukocyte interferon treatment in 14 chronic HBsAg-, HBeAg-, hepatitis B virus DNA-and DNA polymerasepositive carriers. a-Interferon was administered for 9 weeks. Six of 14 treated carriers have a sustained loss of HBe