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Treatment of advanced head and neck cancer with concomitant radiation and chemotherapy

✍ Scribed by Anantha K. Murthy; Samuel G. Taylor IV; John Showel; David D. Caldarelli; James C. Hutchinson Jr.; Lauren D. Holinger; Thomas R. Witt; Stanley Hoover

Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
923 KB
Volume
13
Category
Article
ISSN
0360-3016

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## Abstract Three patients with locally advanced head and neck squamous cell cancer received concomitant radiation therapy (XRT) and cis‐diamminedichloroplatinum (CDDP). The dose of 6,000 rads was to be administered in two 3,000‐rad courses separated by 3 weeks. The CDDP, 30 mg/m^2^, was to be give

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Induction (proto) chemotherapy consisting of 3 courses of cisplatin and 120-hour 5-fluorouracil infusion was administered to 88 patients who had locally advanced, previously untreated head and neck cancer. The majority (81%) of these patients were classified as stage IV, and 17% had second primary c