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Trastuzumab Emtansine for HER2-Positive Advanced Breast Cancer

✍ Scribed by Verma, Sunil; Miles, David; Gianni, Luca; Krop, Ian E.; Welslau, Manfred; Baselga, José; Pegram, Mark; Oh, Do-Youn; Diéras, Véronique; Guardino, Ellie; Fang, Liang; Lu, Michael W.; Olsen, Steven; Blackwell, Kim

Book ID
120008344
Publisher
Massachusetts Medical Society
Year
2012
Tongue
English
Weight
365 KB
Volume
367
Category
Article
ISSN
0096-6762

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## Background: Patients with progressive disease after two or more her2-directed regimens for recurrent or metastatic breast cancer have few effective therapeutic options. we aimed to compare trastuzumab emtansine, an antibody-drug conjugate comprising the cytotoxic agent dm1 linked to trastuzumab,