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Trastuzumab emtansine versus treatment of physician's choice for pretreated HER2-positive advanced breast cancer (TH3RESA): a randomised, open-label, phase 3 trial

✍ Scribed by Krop, Ian E; Kim, Sung-Bae; González-Martín, Antonio; LoRusso, Patricia M; Ferrero, Jean-Marc; Smitt, Melanie; Yu, Ron; Leung, Abraham C F; Wildiers, Hans


Book ID
122183443
Publisher
The Lancet
Year
2014
Tongue
English
Weight
422 KB
Volume
15
Category
Article
ISSN
1470-2045

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Trastuzumab emtansine versus treatment o
✍ Krop, Ian E; Kim, Sung-Bae; González-Martín, Antonio; LoRusso, Patricia M; Ferre 📂 Article 📅 2014 🏛 The Lancet 🌐 English ⚖ 422 KB

## Background: Patients with progressive disease after two or more her2-directed regimens for recurrent or metastatic breast cancer have few effective therapeutic options. we aimed to compare trastuzumab emtansine, an antibody-drug conjugate comprising the cytotoxic agent dm1 linked to trastuzumab,