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Trapping of Methylglyoxal by Curcumin in Cell-Free Systems and in Human Umbilical Vein Endothelial Cells

โœ Scribed by Hu, Te-Yu; Liu, Cheng-Ling; Chyau, Charng-Cherng; Hu, Miao-Lin

Book ID
111980140
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
867 KB
Volume
60
Category
Article
ISSN
0021-8561

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## Abstract Hyperglycemia and elevation of methylglyoxal (MG) are symptoms of diabetes mellitus (DM). We previously showed that high glucose (HG; 30 mM) or MG (50โ€“400 ยตM) could induce apoptosis in mammalian cells, but these doses are higher than the physiological concentrations of glucose and MG in