Transspecific variability of mitochondrial NAD-malate dehydrogenase (E.C.: 1.1.1.37) in Primates
✍ Scribed by Schmitt, J. ;K�mpf, J. ;Ritter, H.
- Publisher
- Springer-Verlag
- Year
- 1971
- Weight
- 151 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0018-7348
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✦ Synopsis
The genetic polymorphism of mitochondrial NAD-malate dehydrogenase has been investigated in Primates. 3 enzyme variants could be demonstrated.
Zusammen/assung. Die mitoehondriale NAD-Malatdehydrogenase der Primaten zeigt eine genetisch determinierte Variabilit~it. Es konnten 3 Enzymvarianten nachgewiesen werden.
In recent years it has been shown that two seperable forms of NAD-malate dehydrogenase (L-malate : NAD oxidorcduetase) occur in a variety of mammalian tissues, one of which is in the cytoplasm as a soluble enzyme and the other is associated with the mitochondria. Each of these enzymes has a characteristic electrophoretic pattern. Transspecifie variability of the soluble NAD-malate dehydrogenase (s-MDH) in Primates was demonstrated by Tariverdian et al. (1971). This report concerns genetic polymorphism of the mitochondrial NADmalate dehydrogenase (m-MDI-I) in Primates.
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