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Transspecific variability of mitochondrial NAD-malate dehydrogenase (E.C.: 1.1.1.37) in Primates

✍ Scribed by Schmitt, J. ;K�mpf, J. ;Ritter, H.


Publisher
Springer-Verlag
Year
1971
Weight
151 KB
Volume
13
Category
Article
ISSN
0018-7348

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✦ Synopsis


The genetic polymorphism of mitochondrial NAD-malate dehydrogenase has been investigated in Primates. 3 enzyme variants could be demonstrated.

Zusammen/assung. Die mitoehondriale NAD-Malatdehydrogenase der Primaten zeigt eine genetisch determinierte Variabilit~it. Es konnten 3 Enzymvarianten nachgewiesen werden.

In recent years it has been shown that two seperable forms of NAD-malate dehydrogenase (L-malate : NAD oxidorcduetase) occur in a variety of mammalian tissues, one of which is in the cytoplasm as a soluble enzyme and the other is associated with the mitochondria. Each of these enzymes has a characteristic electrophoretic pattern. Transspecifie variability of the soluble NAD-malate dehydrogenase (s-MDH) in Primates was demonstrated by Tariverdian et al. (1971). This report concerns genetic polymorphism of the mitochondrial NADmalate dehydrogenase (m-MDI-I) in Primates.


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