๐”– Bobbio Scriptorium
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Transporter molecules in multidrug resistance

โœ Scribed by Rik J. Scheper; George L. Scheffer; Marcel J. Flens; Paul Valk; Henk J. Broxterman; Miguel A. Izquierdo

Publisher
Springer
Year
1996
Tongue
English
Weight
321 KB
Volume
19
Category
Article
ISSN
0920-9069

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Resistance to multiple natural product drugs associated with reduced drug accumulation in human tumor cells may be conferred by either the 170 kDa P-glycoprotein or the 190 kDa multidrug resistance protein, MRP. Both MRP and P-glycoprotein belong to the large and ancient ATP-binding cassette (ABC) s