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Transport mechanisms of flavanone aglycones across Caco-2 cell monolayers and artificial PAMPA membranes

✍ Scribed by Shoko Kobayashi; Toshitada Nagai; Yutaka Konishi; Soichi Tanabe; Kaori Morimoto; Takuo Ogihara

Book ID
118111599
Publisher
Pharmaceutical Press
Year
2011
Tongue
English
Weight
359 KB
Volume
64
Category
Article
ISSN
2042-7158

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✍ Han-Joo Maeng; Ho-Jung Yoo; In-Wha Kim; Im-Sook Song; Suk-Jae Chung; Chang-Koo S πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 116 KB

The objective of this study was to investigate the mechanisms by which berberine is transported in the secretory and absorptive directions across Caco-2 cell monolayers. The basolateral-to-apical (B-A) flux was 30-fold greater than the apical-to-basolateral flux and temperature dependent (i.e., dras