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Transport and metabolism of MitoQ10, a mitochondria-targeted antioxidant, in Caco-2 cell monolayers

✍ Scribed by Yan Li; J. Paul Fawcett; Hu Zhang; Ian G. Tucker

Book ID
111770668
Publisher
Pharmaceutical Press
Year
2007
Tongue
English
Weight
447 KB
Volume
59
Category
Article
ISSN
2042-7158

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The objective of this study was to investigate the mechanisms by which berberine is transported in the secretory and absorptive directions across Caco-2 cell monolayers. The basolateral-to-apical (B-A) flux was 30-fold greater than the apical-to-basolateral flux and temperature dependent (i.e., dras