In vivo methotrexate transport in murine
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K. H. Yang; W. P. Fung; R. J. Lutz; R. L. Dedrick; D. S. Zaharko
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Article
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1979
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John Wiley and Sons
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English
β 531 KB
Methotrexate uptake by murine Lewis lung tumor was measured in vivo over a wide dose range. The data were analyzed according to a model previously developed for tissues in which methotrexate uptake is rate limited by transport across the cell membrane. Methotrexate transport in this tumor followed M