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Transplacental pharmacokinetics of the new fluoroquinolone DW-116 in pregnant rats

โœ Scribed by Jong-Choon Kim; Chun-Sik Bae; Sung-Ho Kim; Hyo-In Yun; Seung-Chun Park; Ho-Chul Shin; Junghee Han; Moon-Koo Chung

Book ID
119537585
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
166 KB
Volume
142
Category
Article
ISSN
0378-4274

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Developmental toxicity assessment of the new ๏ฌ‚uoroquinolone antibacterial DW-116 in rabbits
โœ J. C. Kim; S. H. Kim; D. H. Shin; C. S. Bae; K. S. Oh; J. H. Kim; H. I. Yun; J. ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 90 KB

## Abstract DWโ€116 is a newly developed ๏ฌ‚uoroquinolone antibacterial with a broad spectrum against both Gramโ€positive and Gramโ€negative bacteria. We have reported recently that DWโ€116 is embryotoxic and teratogenic in rats. The present study was conducted to investigate the teratogenicity of DWโ€116