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Fetal and maternal tissue distribution of the new fluoroquinolone DW-116 in pregnant rats

โœ Scribed by Ho-Chul Shin; Jong-Choon Kim; Moon-Koo Chung; Yong-Ho Jung; Jin-Suk Kim; Mi-Kyung Lee; Gordon L. Amidon


Book ID
116346690
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
134 KB
Volume
136
Category
Article
ISSN
1532-0456

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## Abstract DWโ€116 is a newly developed ๏ฌ‚uoroquinolone antibacterial with a broad spectrum against both Gramโ€positive and Gramโ€negative bacteria. We have reported recently that DWโ€116 is embryotoxic and teratogenic in rats. The present study was conducted to investigate the teratogenicity of DWโ€116