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Transplacental effects of nitrosamines in Syrian hamsters

โœ Scribed by J. Althoff; C. Grandjean; S. Marsh; P. Pour; M. Takahashi


Book ID
112289641
Publisher
Springer-Verlag
Year
1977
Tongue
English
Weight
416 KB
Volume
90
Category
Article
ISSN
1432-1335

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Administration o f the nitrosamine carcinogen N-nitroso-bis (2-oxopropy 1) amine (BOP) by subcutaneous injection (5 mg/kg/week) led to the development of invasive pancreatic ductular adenocarcinoma in 100% of normal Syrian hamsters by 24 weeks. Pretreatment of a second group of hamsters with the bet