𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Transmission of mental retardation with fragile X site by two normal transmitter brothers

✍ Scribed by Pellissier, Marie-Christine ;Voelckel, Marie-Antoinette ;Piquet, Caroline ;Mattei, Marie-Geneviève ;Mattei, Jean-François


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
403 KB
Volume
38
Category
Article
ISSN
0148-7299

No coin nor oath required. For personal study only.

✦ Synopsis


We report clinical, chromosomal, and DNA studies in 32 individuals in a family with mental retardation associated with the fragile X chromosome transmitted through 2 normal transmitter brothers.


📜 SIMILAR VOLUMES


DNA studies of X-linked mental retardati
✍ Davies, Kay E. ;Opitz, John M. ;Reynolds, James F. 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 420 KB 👁 2 views

Linkage a n a l y s i s i n a f f e c t e d f a m i l i e s i n d i c a t e s a h i g h frequency of recombination around t h i s s i t e i n some f a m i l i e s , a l t h o u g h i n o t h e r s t h e g e n e t i c r e l a t i o n s h i p s a r e q u i t e d i f f e r e n t and c l o s e r l i n k

Fragile X expression in normal and menta
✍ Sanfilippo, S. ;Ragusa, R. M. ;Scillato, F. ;Ruggeri, M. ;Neri, G. 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 285 KB 👁 1 views

Expression of the fragile site fra(X) ( q 2 7 . 3 ) in peripheral lymphocytes was evaluated in mentally retarded patients and in normal control individuals before and after administration of the antifolic agent trimethoprim for 7 days. This treatment was effective in converting the status of some in