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Translocation (X;8)(q2?6;q21.3) in a case of systemic mastocytosis

✍ Scribed by Yanming Zhang; Brigitte Schlegelberger; Klaus Weber-Matthiesen; Werner Grote; Heinrich Bartels

Book ID
113253480
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
222 KB
Volume
78
Category
Article
ISSN
0165-4608

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A new case of translocation t(6;11)(q21;q23) in a patient with therapy-related acute myeloblastic leukemia is reported. The translocation results in fusion of the MLL and AF6q21 genes. The breakpoint with AF6q21 is located within the sequences encoding the AF6q21 fork head motif. The similar locatio