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Translocation t(8;16) in acute monocytic leukemia

✍ Scribed by Reinhard Becher; Oskar A. Haas; Ullrich Graeven; Peter Bettelheim; Peter Ambros; Michael Fridrik; Ulrich W. Schaefer; Carl G. Schmidt


Book ID
119103992
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
382 KB
Volume
34
Category
Article
ISSN
0165-4608

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Using a series of yeast artificial chromosomes (YAC) from the 8p I I -I 2 chromosome region, we have analyzed a t(822) translocation present in two patients suffering from acute leukemia by using fluorescence in situ hybridization (FISH). We have identified a YAC that spans the breakpoint in both ca