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Translocation t(1;3)(p36;q21) in malignant myeloid stem cell disorders

✍ Scribed by Giovanna Rege Cambrin; Cristina Mecucci; Angeline Van Orshoven; Guido Tricot; Herman Van den Berghe

Book ID: 119103260
Publisher: Elsevier Science
Year: 1986
Tongue: English
Weight: 452 KB
Volume: 22
Category: Article
ISSN: 0165-4608
DOI: 10.1016/0165-4608(86)90140-8

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The reciprocal translocation t(1;3)(p36;q21) is associated with myelodysplastic syndromes (MDSs) and acute myeloid leukemia (AML) characterized by trilineage dysplasia, in particular dysmegakaryocytopoiesis, and a poor prognosis. As yet no molecular genetic analyses of the t(1;3) have been reported.