Translocation t(13;14) in nine generations with a case of translocation homozygosity
✍ Scribed by A. Eklund; K. O. J. Simola; M. Ryynänen
- Book ID
- 115089761
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 222 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0009-9163
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## Abstract Cytogenetic studies of a rhabdomyosarcoma of mixed embryonal and alveolar histology in an II ‐month‐old male revealed a single structural abnormality, t(1;13)(p36;q14). This abnormality may define a subset of patients with a variant of the t(2;13)(q35;q14) translocation frequently seen
A Robertsonian translocation 45,XY, t(13q;14q) was detected in the leukocyte cultures of a phenotypically normal male. Silver staining technique for nucleolus organizer regions revealed that both acrocentrics involved in the translocation had lost their nucleolus organizers.