Translocation of c-abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia
โ Scribed by Bartram, Claus R.; de Klein, Annelies; Hagemeijer, Anne; van Agthoven, Ton; van Kessel, Ad Geurts; Bootsma, Dirk; Grosveld, Gerard; Ferguson-Smith, Malcolm A.; Davies, Teresa; Stone, Marion
- Book ID
- 109732719
- Publisher
- Nature Publishing Group
- Year
- 1983
- Tongue
- English
- Weight
- 470 KB
- Volume
- 306
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/306277a0
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract We have sought to define the relationship between the proportion of marrow metaphases showing the Philadelphia chromosome (Ph) and levels of __BCRโABL__ mRNA assessed by quantitative polymerase chain reaction (PCR) in patients with chronic myeloid leukaemia (CML). From a total of 141 pa
## Abstract Chromosome aberrations are frequently found in Bโcell chronic lymphocytic leukaemia (BโCLL), and specific chromosome aberrations identify poor prognostic subgroups. Almost all the aberrations identified in BโCLL involve loci where genes with a role in the regulation of centrosome duplic