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Translocation (3;14)(q27;q11): A new variant translocation in a patient with non-Hodgkin's lymphoma of B-cell type with BCL6 rearrangement

✍ Scribed by Naoto Takahashi; Ikuo Miura; Atsushi Ohshima; Seiko Utsumi; Takashi Nimura; Keiko Hashimoto; Akihiko Cyubachi; Masahiro Saitoh; Katsuhiko Enomoto; Tohru Miki; Shinsaku Hirosawa; Akira Miura


Book ID
113253792
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
755 KB
Volume
90
Category
Article
ISSN
0165-4608

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The LAZ3(BCL6) gene on chromosome band 3q27 is nonrandomly disrupted in B-cell non-Hodgkin lymphoma (B-NHL) by chromosomal translocations clustered within a 3.3-kb MTC (major translocation cluster) located between the two first noncoding exons. These translocations generally result in the expression