Transition structures for the dieckmann condensation
β Scribed by Tamiki Nishimura; Makoto Sunagawa; Toshiya Okajima; Yoshimasa Fukazawa
- Book ID
- 104257966
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 209 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
Burinsky and Cooks' have reported that deprotonated dimethyl adipate eliminates methanol via a gas-phase Dieckmann condensation. This is in contrast to the behaviour of simple methyl ester enolates which lose MeOH by a different mechanism, e.g. MeOCOCHCH,R + [M&(OCCHCH,R)] + O-C-CHCHR + MeOH. Eviden
## Abstract (__R__)βReutericyclin ((__R__)β**1**), a bactericidal, amphiphilic natural product with a trisubstituted tetramic acid moiety, was prepared in four steps from Dβleucine in an overall yield of 24%. The chiral heterocyclic portion of **1** was synthesized by __Dieckmann__ cyclization of e