Transition states of native and drug-resistant HIV-1 protease are the same
β Scribed by Kipp, D. R.; Hirschi, J. S.; Wakata, A.; Goldstein, H.; Schramm, V. L.
- Book ID
- 111644143
- Publisher
- National Academy of Sciences
- Year
- 2012
- Tongue
- English
- Weight
- 927 KB
- Volume
- 109
- Category
- Article
- ISSN
- 0027-8424
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Novel HIV-1 protease inhibitors have been prepared in a enantioselective manner via an Evans asymmetric aldol, Claisen rearrangement and icdolactonization. X-ray crystallographic analysis was used to confirm the absolute configuration of the newly created stereogenic centers. The alarming spread of