Transition Metal Complexes in Organic Synthesis. Part 61: Convergent Synthesis of Indolo[2,3-b]carbazole by an Iron-Mediated Bidirectional Annulation of Two Indole Rings
✍ Scribed by Hans-Joachim Knölker; Kethiri R. Reddy
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 117 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0040-4020
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✦ Synopsis
AbstractÐA highly convergent synthesis provides indolo [2,3-b]carbazole in two steps and 36% overall yield from commercial m-phenylenediamine by a double iron-mediated consecutive C±C and C±N bond formation featuring the ®rst double iron-mediated arylamine cyclization.
📜 SIMILAR VOLUMES
A straightforward two-step synthesis of indolo[2,3-b]carbazole using a double iron-mediated arylamine eyelization as the key-step is described.
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þ)-Demethoxycarbonyldihydrogambirtannine was obtained in six steps and 49% overall yield from 3,4-dihydro-b-carboline using an iron-mediated [2+2+1] cycloaddition as the key-step. Oxidation of (þ)-demethoxycarbonyldihydrogambirtannine led to norketoyobyrine.