Transition metal alkyne complexes: the Pauson–Khand reaction

✍ Scribed by Young Keun Chung

• Book ID: 104111924
• Publisher: Elsevier Science
• Year: 1999
• Tongue: English
• Weight: 859 KB
• Volume: 188
• Category: Article
• ISSN: 0010-8545
• DOI: 10.1016/s0010-8545(99)00032-6

✦ Synopsis

The Pauson-Khand reaction (PKR) is a cocyclization of alkynes with alkenes and carbon monoxide by dicobalt octacarbonyl leading to cyclopentenones and has become one of the most useful methods for the synthesis of cyclopentenone. However, most of the known PKRs were stoichiometric and slow reactions. Thus, several promoters were reported to promote the PKR. Recently the catalytic version of PKR has been revealed. A number of variation with different transition-metals appeared. Most of the reactions studied are not asymmetric. However, asymmetric PKRs appeared. The utilization of the PKR in organic chemistry is quite general. Recently, the utilization of the PKR products in the synthesis of www.elsevier.com/locate/ccr