Southern blot-hybridization analysis of 10 breast carcinoma cell lines demonstrated an amplification of the epidermal growth factor (EGF) receptor gene in the BTZO cell line. The gene was amplified 10to 14-fold when compared to the level seen in human placental DNA. Northern blot analysis indicated
✦ LIBER ✦
Transient transfection of epidermal growth factor receptor gene into MCF7 breast ductal carcinoma cell line
✍ Scribed by Majed S. Alokail
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 743 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0263-6484
- DOI
- 10.1002/cbf.1186
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A number of studies suggest that an inverse correlation exists between the epidermal growth factor-receptor and the estrogen receptor expression in primary human breast carcinoma as well as in established human breast carcinoma cell lines. Recent studies suggest that the epidermal growth factor-rece