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Transient myeloproliferative disorder progression and acquired chromosomal abnormalities in children with Down syndrome

✍ Scribed by Verónica Judith Picos Cárdenas; Juan Pablo Meza Espinoza; Roberto Francisco Garibaldi Covarrubias; Reyna Lucía Barajas Torres; Juan Ramón González García


Book ID
112168246
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
41 KB
Volume
59
Category
Article
ISSN
1545-5009

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## Abstract An infant with Down syndrome (DS) and RH isoimmunization developed transient myeloproliferative disorder (TMD) during the neonatal period. At 16 months she presented with acute nonlymphocytic leukemia (ANLL). Cytogenetic studies during TMD showed trisomy 21 only but new abnormalities em